Multimer Formation Explains Allelic Suppression of PRDM9 Recombination Hotspots.
Genetic recombination during meiosis functions to increase genetic diversity, promotes elimination of deleterious alleles, and helps assure proper segregation of chromatids. Mammalian recombination events are concentrated at specialized sites, termed hotspots, whose locations are determined by PRDM9...
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| Үндсэн зохиолчид: | , , , , , , , |
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| Формат: | Artigo |
| Хэл сонгох: | Inglês |
| Хэвлэсэн: |
Public Library of Science (PLoS)
2015-09-01
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| Цуврал: | PLoS Genetics |
| Онлайн хандалт: | http://europepmc.org/articles/PMC4569383?pdf=render |
| Шошгууд: |
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