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Association between gut microbiota and gastrointestinal cancer: a two-sample bi-directional Mendelian randomization study

BackgroundThe gut microbiome is closely related to gastrointestinal (GI) cancer, but the causality of gut microbiome with GI cancer has yet to be fully established. We conducted this two-sample Mendelian randomization (MR) study to reveal the potential causal effect of gut microbiota on GI cancer.Ma...

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Principais autores: Qing Su, Chen Jin, Zhiyuan Bo, Yi Yang, Jingxian Wang, Juejin Wang, Junxi Zhou, Yaqing Chen, Hao Zeng, Gang Chen, Yi Wang
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2023-07-01
Serier:Frontiers in Microbiology
Fag:
gut microbiota
gastrointestinal cancer
Mendelian randomization
instrumental variable
causal relationship
Online adgang:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1181328/full
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