Hydroxypropyl-β-Cyclodextrin Depletes Membrane Cholesterol and Inhibits SARS-CoV-2 Entry into HEK293T-ACE^hi Cells

Vaccination has drastically decreased mortality due to coronavirus disease 19 (COVID-19), but not the rate of acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Alternative strategies such as inhibition of virus entry by interference with angiotensin-I-converting enzyme 2 (ACE2) recept...

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Detalhes bibliográficos

Principais autores:	Silvia Alboni, Valentina Secco, Bianca Papotti, Antonietta Vilella, Maria Pia Adorni, Francesca Zimetti, Laurent Schaeffer, Fabio Tascedda, Michele Zoli, Pascal Leblanc, Erica Villa
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2023-04-01
coleção:	Pathogens
Assuntos:	SARS-CoV-2 cyclodextrin lipid raft cholesterol prophylaxis
Acesso em linha:	https://www.mdpi.com/2076-0817/12/5/647
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