Differential GC Content between Exons and Introns Establishes Distinct Strategies of Splice-Site Recognition

During evolution segments of homeothermic genomes underwent a GC content increase. Our analyses reveal that two exon-intron architectures have evolved from an ancestral state of low GC content exons flanked by short introns with a lower GC content. One group underwent a GC content elevation that abo...

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Autori principali:	Maayan Amit, Maya Donyo, Dror Hollander, Amir Goren, Eddo Kim, Sahar Gelfman, Galit Lev-Maor, David Burstein, Schraga Schwartz, Benny Postolsky, Tal Pupko, Gil Ast
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2012-05-01
Serie:	Cell Reports
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2211124712000988
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