Eltroxin and Hesperidin mitigate testicular and renal damage in hypothyroid rats: amelioration of oxidative stress through PPARγ and Nrf2/HO-1 signaling pathway

Abstract Background Thyroid hormones (THs) regulate growth, development and function of different tissues. Hypothyroidism is a common clinical disorder characterized by deficiency in THs and adversely affects the development and functions of several organs. This work aimed to investigate the amelior...

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Главные авторы:	Hadeel M. Osama, Sally M. Khadrawy, EL-Shaymaa EL-Nahass, Sarah I. Othman, Hanaa M. Mohamed
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2024-05-01
Серии:	Laboratory Animal Research
Предметы:	Hesperidin Hypothyroidism Testis Kidney Nrf2/HO-1 PPARγ
Online-ссылка:	https://doi.org/10.1186/s42826-024-00204-8
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