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Induction of Autoimmune Myocarditis in Diversity Outbred Mice

Background. Inbred mouse models of autoimmune myocarditis are routinely used to investigate the immune mechanisms underlying dilated cardiomyopathy. However, their translational relevance is limited because observations made in a single inbred strain may not reflect those of outbred human population...

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Autori principali: Meghna Sur, Kiruthiga Mone, Shraddha Singh, Mahima T. Rasquinha, Jean-Jack M. Riethoven, Indranil Mukhopadhyay, Raymond A. Sobel, Jay Reddy
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2026-02-01
Serie:Biology
Soggetti:
porcine cardiac myosin
myocarditis
mouse models
diversity outbred
immune cells
dilated cardiomyopathy
Accesso online:https://www.mdpi.com/2079-7737/15/3/288
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