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Prognostic tumor sequencing panels frequently identify germ line variants associated with hereditary hematopoietic malignancies

Abstract: Next-generation sequencing (NGS)–based targeted gene capture panels are used to profile hematopoietic malignancies to guide prognostication and treatment decisions. Because these panels include genes associated with hereditary hematopoietic malignancies (HHMs), we hypothesized that these p...

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Principais autores: Michael W. Drazer, Sabah Kadri, Madina Sukhanova, Sushant A. Patil, Allison H. West, Simone Feurstein, Dalein A. Calderon, Matthew F. Jones, Caroline M. Weipert, Christopher K. Daugherty, Adrián A. Ceballos-López, Gordana Raca, Mark W. Lingen, Zejuan Li, Jeremy P. Segal, Jane E. Churpek, Lucy A. Godley
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2018-01-01
Series:Blood Advances
Acceso en liña:http://www.sciencedirect.com/science/article/pii/S2473952920311241
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