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Population HLA coverage of experimentally characterized P. falciparum CD8+ T cell epitopes as potential components of a multi-epitope malaria vaccine construct: an in silico insight

ObjectiveMalaria remains a significant global health challenge, with Plasmodium falciparum causing the most severe cases and deaths, particularly in sub-Saharan Africa. An effective universal or pan vaccine is needed to augment current concerted control efforts. This in silico study investigated the...

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Principais autores: Courage Siame, Rafiatu Abdul-Mumin, Georgina Agyekum, Linda Akuffo, Ernest Afari, Cecilia Adwoa Biaa Yankey, Kwadwo Asamoah Kusi
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2026-03-01
Serier:Frontiers in Bioinformatics
Fag:
epitope prediction
HLA
immune epitope database
malaria
P. falciparum
Online adgang:https://www.frontiersin.org/articles/10.3389/fbinf.2026.1722563/full
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