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Dysregulated Glucuronidation of Bilirubin Exacerbates Liver Inflammation and Fibrosis in Schistosomiasis Japonica through the NF-κB Signaling Pathway

Hepatic fibrosis is an important pathological manifestation of chronic schistosome infection. Patients with advanced schistosomiasis show varying degrees of abnormalities in liver fibrosis indicators and bilirubin metabolism. However, the relationship between hepatic fibrosis in schistosomiasis and...

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Principais autores: Qingkai Xue, Yuyan Wang, Yiyun Liu, Haiyong Hua, Xiangyu Zhou, Yongliang Xu, Ying Zhang, Chunrong Xiong, Xinjian Liu, Kun Yang, Yuzheng Huang
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2024-03-01
Serier:Pathogens
Fag:
<i>Schistosoma japonicum</i>
hepatic fibrosis
UGT1A1
bilirubin
NF-κB
Online adgang:https://www.mdpi.com/2076-0817/13/4/287
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