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Exploring the protective role of DDIT4/mTOR in podocyte integrity through macrophage polarization in diabetic kidney disease

Objectives In this study, we explored the mechanism by which DDIT4 influences the polarization phenotypic transformation of macrophages and inflammation through the regulation of mTOR signaling pathway, providing a new mechanism and target for the treatment of diabetic nephropathy.Methods The degree...

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Bibliografiske detaljer
Principais autores: Jingxuan Shi, Xiansen Wei, Guming Zou, Xinze Liu, Jiaqi An, Qiaoya He, Yuanyuan Jiao, Jingwei Tian, Yue Yang, Li Zhuo, Wenge Li
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2025-12-01
Serier:Renal Failure
Fag:
Online adgang:https://www.tandfonline.com/doi/10.1080/0886022X.2025.2546623
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