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Identification of RTS,S/AS01 vaccine–induced humoral biomarkers predictive of protection against controlled human malaria infection

BACKGROUND The mechanism(s) responsible for the efficacy of WHO-recommended malaria vaccine RTS,S/AS01 are not completely understood. We previously identified RTS,S vaccine–induced Plasmodium falciparum circumsporozoite protein–specific (PfCSP-specific) antibody measures associated with protection f...

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Библиографические подробности
Главные авторы: Rachel L. Spreng, Kelly E. Seaton, Lin Lin, Sir’Tauria Hilliard, Gillian Q. Horn, Milite Abraha, Aaron W. Deal, Kan Li, Alexander J. Carnacchi, Elizabeth Feeney, Siam Shabbir, Lu Zhang, Valerie Bekker, Sarah V. Mudrak, Sheetij Dutta, Laina D. Mercer, Scott Gregory, C. Richter King, Ulrike Wille-Reece, Erik Jongert, Neville K. Kisalu, Georgia D. Tomaras, S. Moses Dennison
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical investigation 2024-10-01
Серии:JCI Insight
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Online-ссылка:https://doi.org/10.1172/jci.insight.178801
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