Mechanisms of Mitotic Kinase Regulation: A Structural Perspective
Protein kinases are major regulators of mitosis, with over 30% of the mitotic proteome phosphorylated on serines, threonines and tyrosines. The human genome encodes for 518 kinases that have a structurally conserved catalytic domain and includes about a dozen of cell division specific ones. Yet each...
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| Principais autores: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Frontiers Media S.A.
2018-02-01
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| Series: | Frontiers in Cell and Developmental Biology |
| Assuntos: | |
| Acceso en liña: | http://journal.frontiersin.org/article/10.3389/fcell.2018.00006/full |
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