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Direct Enzymatic Route for the Preparation of Novel Enantiomerically Enriched Hydroxylated β-Amino Ester Stereoisomers

Enantiomerically enriched hydroxy-substituted b-amino esters have been synthesized through CAL-B-catalyzed enantioselective hydrolysis in organic media. Moderate to good enantiomeric excess values (ee ≥ 52%) were obtained when the CAL-B-catalyzed reactions were performed in t-BuOMe, at 60 ºC with 0....

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Detalhes bibliográficos
Principais autores: Enikő Forró, László Schönstein, Loránd Kiss, Alberto Vega-Peñaloza, Eusebio Juaristi, Ferenc Fülöp
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2010-06-01
coleção:Molecules
Assuntos:
Acesso em linha:http://www.mdpi.com/1420-3049/15/6/3998/
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