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TNFα induces Caspase-3 activity in hematopoietic progenitor cells CD34+, CD33+, and CD41 + of myelodysplastic syndromes

Abstract Background Cytopenia is the primary feature of Myelodysplastic Syndrome, even in the presence of hypercellular bone marrow. TNFα is recognized as both a proinflammatory, and proapoptotic cytokine with a well established role in promoting apoptosis in MDS. Therefore, TNFα has the potential t...

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Principais autores: Anggraini Iriani, Andhika Rachman, Rahayuningsih D. Setiabudy, Siti B. Kresno, Aru W. Sudoyo, Mansyur Arief, Alida R. Harahap, Marsya Kaila Fatina
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2023-11-01
Serier:BMC Molecular and Cell Biology
Fag:
Myelodysplastic syndrome
TNFα
caspase-3
CD34+
CD33+
CD41+
Online adgang:https://doi.org/10.1186/s12860-023-00495-0
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