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Mitochondrial lipidomes are tissue specific – low cholesterol contents relate to UCP1 activity

The mitochondria’s lipid composition is key for brown adipose tissue function. High cholesterol contents block UCP1 activity, whereas increasing phosphatidyl-choline and -ethanolamine levels boost it. Lipid composition is conserved within sub-cellular compartments to maintain cell function. Lipidomi...

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Hlavní autoři: Sarah Brunner, Marcus Höring, Gerhard Liebisch, Sabine Schweizer, Josef Scheiber, Piero Giansanti, Maria Hidrobo, Sven Hermeling, Josef Oeckl, Natalia Prudente de Mello, Fabiana Perocchi, Claudine Seeliger, Akim Strohmeyer, Martin Klingenspor, Johannes Plagge, Bernhard Küster, Ralph Burkhardt, Klaus-Peter Janssen, Josef Ecker
Médium: Artigo
Jazyk:Inglês
Vydáno: Life Science Alliance LLC 2024-08-01
Edice:Life Science Alliance
On-line přístup:https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202402828
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