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Butanolides and Butenolides from a Marine-Derived <i>Streptomyces</i> sp. Exert Neuroprotective Activity through Activation of the TrkB Neurotrophin Receptor

Neurodegenerative diseases are incurable and debilitating conditions, characterized by progressive loss and degeneration of vulnerable neuronal populations. Currently, there are no effective therapies available for the treatment of most neurodegenerative disorders. A panel of extracts exhibiting int...

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Principais autores: Paolo Giaccio, Despoina Charou, Dafni-Ioanna Diakaki, Anna Chita, Achille Gravanis, Ioannis Charalampopoulos, Vassilios Roussis, Efstathia Ioannou
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2023-08-01
Series:Marine Drugs
Assuntos:
marine actinobacteria
<i>Streptomyces</i>
γ-lactones
neurodegenerative diseases
neuroprotection
TrkB receptor
Acceso en liña:https://www.mdpi.com/1660-3397/21/9/465
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