Exercise intolerance and rapid skeletal muscle energetic decline in human age-associated frailty
BACKGROUND Physical frailty in older individuals is characterized by subjective symptoms of fatigue and exercise intolerance (EI). Objective abnormalities in skeletal muscle (SM) mitochondrial high-energy phosphate (HEP) metabolism contribute to EI in inherited myopathies; however, their presence or...
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| Principais autores: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical investigation
2020-10-01
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| coleção: | JCI Insight |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1172/jci.insight.141246 |
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