Directed differentiation of human iPSCs to functional ovarian granulosa-like cells via transcription factor overexpression

An in vitro model of human ovarian follicles would greatly benefit the study of female reproduction. Ovarian development requires the combination of germ cells and several types of somatic cells. Among these, granulosa cells play a key role in follicle formation and support for oogenesis. Whereas ef...

Полное описание

Библиографические подробности

Главные авторы:	Merrick D Pierson Smela, Christian C Kramme, Patrick RJ Fortuna, Jessica L Adams, Rui Su, Edward Dong, Mutsumi Kobayashi, Garyk Brixi, Venkata Srikar Kavirayuni, Emma Tysinger, Richie E Kohman, Toshi Shioda, Pranam Chatterjee, George M Church
Формат:	Artigo
Язык:	Inglês
Опубликовано:	eLife Sciences Publications Ltd 2023-02-01
Серии:	eLife
Предметы:	granulosa oogenesis transcription factors stem cells ovary
Online-ссылка:	https://elifesciences.org/articles/83291
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!