LLDT-8 protects against cerebral ischemia/reperfusion injury by suppressing post-stroke inflammation

Aim: (5R)-5-Hydroxytriptolide (LLDT-8), an analogue of triptolide, displays lower toxicity compared to triptolide and has comparable immunosuppressive effects. We investigated the anti-inflammatory and neuroprotective effects of LLDT-8 on cerebral ischemia/reperfusion injury. Methods: Nitric oxide p...

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Detalhes bibliográficos

Principais autores:	Yanke Chen, Li Zhang, Jingshu Ni, Xiaoyu Wang, Jian Cheng, Yuanchao Li, Xuechu Zhen, Ting Cao, Jia Jia
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2016-06-01
Colecção:	Journal of Pharmacological Sciences
Assuntos:	LLDT-8 Cerebral ischemia Neuroinflammation Microglia
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S134786131630055X
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