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Differential Modulation of IK and ICa,L Channels in High-Fat Diet-Induced Obese Guinea Pig Atria

Obesity mechanisms that make atrial tissue vulnerable to arrhythmia are poorly understood. Voltage-dependent potassium (IK, IKur, and IK1) and L-type calcium currents (ICa,L) are electrically relevant and represent key substrates for modulation in obesity. We investigated whether electrical remodeli...

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Autori principali: Laura Martinez-Mateu, Javier Saiz, Ademuyiwa S. Aromolaran
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019-09-01
Serie:Frontiers in Physiology
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Accesso online:https://www.frontiersin.org/article/10.3389/fphys.2019.01212/full
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