Coaggregation of RNA-binding proteins in a model of TDP-43 proteinopathy with selective RGG motif methylation and a role for RRM1 ubiquitination.

TAR DNA-binding protein 43 (TDP-43) is a major component within ubiquitin-positive inclusions of a number of neurodegenerative diseases that increasingly are considered as TDP-43 proteinopathies. Identities of other inclusion proteins associated with TDP-43 aggregation remain poorly defined. In this...

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Principais autores:	Eric B Dammer, Claudia Fallini, Yair M Gozal, Duc M Duong, Wilfried Rossoll, Ping Xu, James J Lah, Allan I Levey, Junmin Peng, Gary J Bassell, Nicholas T Seyfried
Formato:	Artigo
Idioma:	Inglês
Publicado:	Public Library of Science (PLoS) 2012-01-01
Series:	PLoS ONE
Acceso en liña:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22761693/pdf/?tool=EBI
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