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Effects of Pioglitazone on Stearoyl-CoA Desaturase in Obese Zucker fa/fa Rats

The effects of a peroxisome proliferator activated receptor γ (PPARγ) agonist on hepatic stearoyl-CoA desaturase (SCD) in insulin-resistant and obese Zucker fa/fa rats were studied. The administration of pioglitazone, a PPARγ agonist, to Zucker obese rats greatly improved their insulin sensitivity....

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Tomoaki Toyama, Naomi Kudo, Yasuhide Hibino, Atsushi Mitsumoto, Masazumi Nishikawa, Yoichi Kawashima
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2007-01-01
Schriftenreihe:Journal of Pharmacological Sciences
Online-Zugang:http://www.sciencedirect.com/science/article/pii/S1347861319342628
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