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Specific presynaptic functions require distinct Drosophila Cav2 splice isoforms

At many vertebrate synapses, presynaptic functions are tuned by expression of different Cav2 channels. Most invertebrate genomes contain only one Cav2 gene. The Drosophila Cav2 homolog, cacophony (cac), induces synaptic vesicle release at presynaptic active zones (AZs). We hypothesize that Drosophil...

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Principais autores: Christopher Bell, Lukas Kilo, Daniel Gottschalk, Jashar Arian, Lea Deneke, Hanna Kern, Christof Rickert, Oliver Kobler, Julia Strauß, Martin Heine, Carsten Duch, Stefanie Ryglewski
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications Ltd 2025-02-01
Serier:eLife
Fag:
cacophony
Cav2
alternative splicing
synaptic function
synapse
Online adgang:https://elifesciences.org/articles/100394
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