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Reactive oxygen species-related oxidative changes are associated with splenic lymphocyte depletion in Ebola virus infection

Abstract The dysregulated production of reactive oxygen species (ROS) during viral infections may lead to immune cell death and ineffective host responses. ROS dynamics have been under-investigated in severe Ebola virus disease (EVD), a condition in which hyperinflammation and excessive immune cell...

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Hlavní autoři: Venkatesh Mani, Winston T. Chu, Hee-Jeong Yang, C. Paul Morris, Joseph Laux, Russell Byrum, Kurt Cooper, David X. Liu, Hui Wang, Cristal Johnson, Kyra Hadley, John G. Bernbaum, Randy Hart, Scott M. Anthony, Anthony E. Marketon, Rebecca Bernbaum-Cutler, Bapi Pahar, Gabriella Worwa, Jens H. Kuhn, Ian Crozier, Claudia Calcagno, Eric Gale
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2025-04-01
Edice:npj Imaging
On-line přístup:https://doi.org/10.1038/s44303-025-00079-x
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