Bulk RNA-seq conjoined with ScRNA-seq analysis reveals the molecular characteristics of nucleus pulposus cell ferroptosis in rat aging intervertebral discs

Abstract Objective Recently, several studies have reported that nucleus pulposus (NP) cell ferroptosis plays a key role in IDD. However, the characteristics and molecular mechanisms of cell subsets involved remain unclear. We aimed to define the key factors driving ferroptosis, and the characteristi...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Shipeng Chen, Jiawei Fu, Jiang Long, Chang Liu, Xuezheng Ai, Dan Long, Xue Leng, Yang Zhang, Zhengao Liao, Changqing Li, Yue Zhou, Shiwu Dong, Bo Huang, Chencheng Feng
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	BMC 2025-04-01
Σειρά:	Arthritis Research & Therapy
Θέματα:	IDD NP cells ScRNA-seq Ferroptosis Atf3 Rps6 +/Cxcl1
Διαθέσιμο Online:	https://doi.org/10.1186/s13075-025-03550-7
Ετικέτες:	Προσθήκη ετικέτας Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!