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Urokinase-type plasminogen activator supports liver repair independent of its cellular receptor

<p>Abstract</p> <p>Background</p> <p>The urokinase-type (uPA) and tissue-type (tPA) plasminogen activators regulate liver matrix remodelling through the conversion of plasminogen (Plg) to the active protease plasmin. Based on the efficient activation of plasminogen when uPA is bound to its receptor...

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Principais autores: Bezerra Jorge A, Degen Jay L, Sabla Gregg E, Shanmukhappa Kumar
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2006-11-01
Series:BMC Gastroenterology
Acceso en liña:http://www.biomedcentral.com/1471-230X/6/40
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