p190RhoGAP proteins contain pseudoGTPase domains
A growing number of ‘pseudoenzymes’ with a regulatory role in signal transduction processes but without catalytic activity are being identified. Here, the authors identify two pseudoGTPase domains in p190RhoGAP, characterize them biochemically and structurally and show that they influence RhoGAP act...
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| Principais autores: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Portfolio
2017-09-01
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| Serier: | Nature Communications |
| Online adgang: | https://doi.org/10.1038/s41467-017-00483-x |
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