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Filamentation and biofilm formation are regulated by the phase-separation capacity of network transcription factors in Candida albicans.

The ability of the fungus Candida albicans to filament and form biofilms contributes to its burden as a leading cause of hospital-acquired infections. Biofilm development involves an interconnected transcriptional regulatory network (TRN) consisting of nine transcription factors (TFs) that bind both...

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Hlavní autoři: Collin Ganser, Mae I Staples, Maureen Dowell, Corey Frazer, Joseph Dainis, Shabnam Sircaik, Richard J Bennett
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2023-12-01
Edice:PLoS Pathogens
On-line přístup:https://doi.org/10.1371/journal.ppat.1011833
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