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Transcryptomic Analysis of Human Brain-Microvascular Endothelial Response to -Pericytes: Cell Orientation Defines Barrier Function

Pericytes facilitate blood–brain barrier (BBB) integrity; however, the mechanisms involved remain unclear. Hence, using co-cultures of human cerebral microvascular endothelial cells (ECs) and vascular pericytes (PCs) in different spatial arrangements, as well as PC conditioned media, we investigated...

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Principais autores: Lisa Kurmann, Michal Okoniewski, Omolara O. Ogunshola, Brigitte Leeners, Bruno Imthurn, Raghvendra K. Dubey
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-04-01
Serier:Cells
Fag:
pericyte
hCMEC/D3
co-culture
blood–brain barrier
orientation
transcriptome
Online adgang:https://www.mdpi.com/2073-4409/10/4/963
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