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The Drosophila zinc finger protein trade embargo is required for double strand break formation in meiosis.

Homologous recombination in meiosis is initiated by the programmed induction of double strand breaks (DSBs). Although the Drosophila Spo11 ortholog Mei-W68 is required for the induction of DSBs during meiotic prophase, only one other protein (Mei-P22) has been shown to be required for Mei-W68 to exe...

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Autors principals: Cathleen M Lake, Rachel J Nielsen, R Scott Hawley
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2011-02-01
Col·lecció:PLoS Genetics
Accés en línia:http://europepmc.org/articles/PMC3044681?pdf=render
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