Mechanistic insights of Sargassum polycystum fatty oil compounds in cutaneous melanoma: in vitro, metabolomics guided-network pharmacology, molecular docking and dynamics approach

Background: Cutaneous melanoma remains a global health issue. While lipid-rich oils have long been used in Traditional Chinese Medicine (TCM) for cancer therapy, brown macroalgae Sargassum also provide lipid derivative compounds with therapeutic potential, including in the modulation of skin disease...

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Главные авторы:	Anggit Listyacahyani Sunarwidhi, Agung Endro Nugroho, Sri Widyastuti, Ekowati Chasanah, Ari Hernawan, Eka Sunarwidhi Prasedya
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Elsevier 2025-12-01
Серии:	Pharmacological Research - Modern Chinese Medicine
Предметы:	Cutaneous melanoma Brown macroalgae Fatty oils Metabolomics Network pharmacology Computational analysis
Online-ссылка:	http://www.sciencedirect.com/science/article/pii/S2667142525001472
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