Evaluation of blood MSI burden dynamics to trace immune checkpoint inhibitor therapy efficacy through the course of treatment

Abstract Analysis of serial liquid biopsy (LB) samples has been found to be a promising approach for the monitoring of tumor dynamics in the course of therapy for patients with colorectal cancer (CRC). Currently, somatic mutations are used for tracing the dynamics of the tumor via LB. However, the a...

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Principais autores:	Egor Veselovsky, Alexandra Lebedeva, Olesya Kuznetsova, Daria Kravchuk, Ekaterina Belova, Anastasia Taraskina, Tatiana Grigoreva, Alexandra Kavun, Victoria Yudina, Laima Belyaeva, Vladislav Nikulin, Vladislav Mileyko, Alexey Tryakin, Mikhail Fedyanin, Maxim Ivanov
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Nature Portfolio 2024-10-01
סדרה:	Scientific Reports
נושאים:	Microsatellite instability Colorectal cancer Next-generation sequencing Immunotherapy Liquid biopsy Immune checkpoint inhibitors
גישה מקוונת:	https://doi.org/10.1038/s41598-024-73952-1
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