Somatic gene mutations involved in DNA damage response/Fanconi anemia signaling are tissue- and cell-type specific in human solid tumors

With significant advancements in the study of DNA Damage Response (DDR) and Fanconi Anemia (FA) signaling, we previously introduced the term “FA signaling” to encompass “all signaling transductions involving one or more FA proteins.” This network has now evolved into the largest cellular defense net...

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Principais autores:	Sudhir Kumar Rai, Wei Du, Jun Zhang, Herbert Yu, Youping Deng, Peiwen Fei
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2024-10-01
Colecção:	Frontiers in Medicine
Assuntos:	DNA Damage Response (DDR) Fanconi anemia (FA) signaling genome instability DNA interstrand cross-links somatic mutation ATR BLM
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fmed.2024.1462810/full
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