Regulator of G protein signaling 12 drives inflammatory arthritis by activating synovial fibroblasts through MYCBP2/KIF2A signaling

Synovial fibroblasts are the active and aggressive drivers in the progression of arthritis, but the cellular and molecular mechanisms remain unknown. Here, our results showed that regulator of G protein signaling 12 (RGS12) maintained ciliogenesis in synovial fibroblasts, which is critical for the d...

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Detalhes bibliográficos

Principais autores:	Gongsheng Yuan, Shu-ting Yang, Shuying Yang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2023-03-01
coleção:	Molecular Therapy: Nucleic Acids
Assuntos:	MT: Oligonucleotides: Therapies and Applications regulator of G protein signaling 12 inflammatory arthritis synovial fibroblasts cilia MYCBP2
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2162253122003389
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