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The Adjuvants Polyphosphazene (PCEP) and a Combination of Curdlan Plus Leptin Promote a Th17-Type Immune Response to an Intramuscular Vaccine in Mice

Our aim was to determine whether polyphosphazene (PCEP), Curdlan (β-glucan, a dectin-1 agonist), and Leptin could act as adjuvants to promote a Th17-type adaptive immune response in mice. Mice were vaccinated via the intramuscular route then boosted three weeks later with Ovalbumin plus: PCEP, Lepti...

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Principais autores: Alyssa Chaffey, Glenn Hamonic, Dylan Chand, George K. Mutwiri, Heather L. Wilson
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2021-05-01
coleção:Vaccines
Assuntos:
mice
ovalbumin
cell-mediated immunity
flow cytometry
interleukin-17
Th17-type T cells
Acesso em linha:https://www.mdpi.com/2076-393X/9/5/507
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