METTL3 regulates cartilage development and homeostasis by affecting Lats1 mRNA stability in an m6A-YTHDF2-dependent manner

Summary: Cartilage maintains the structure and function of joints, with disturbances leading to potential osteoarthritis. N6-methyladenosine (m6A), the most widespread post-transcriptional modification in eukaryotes, plays a crucial role in regulating biological processes. While current research has...

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Hlavní autoři:	Rui Sheng, Weikun Meng, Zhong Zhang, Qi Yin, Shuang Jiang, Qiwen Li, Xinyan Gan, Danting Zhang, Zongke Zhou, Shuibin Lin, Mingyue Lyu, Xingmei Yang, Quan Yuan
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2024-08-01
Edice:	Cell Reports
Témata:	CP: Developmental biology CP: Molecular biology
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2211124724008647
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