Kallikrein-related peptidases 6 and 10 are elevated in cerebrospinal fluid of patients with Alzheimer’s disease and associated with CSF-TAU and FDG-PET

Abstract Background Alterations in the expression of human kallikrein-related peptidases (KLKs) have been described in patients with Alzheimer’s disease (AD). We elucidated the suitability of KLK6, KLK8 and KLK10 to distinguish AD from NC and explored associations with established AD biomarkers. Met...

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Автори:	Oliver Goldhardt, Inanna Warnhoff, Igor Yakushev, Ilijana Begcevic, Hans Förstl, Viktor Magdolen, Antoninus Soosaipillai, Eleftherios Diamandis, Panagiotis Alexopoulos, Timo Grimmer
Формат:	Artigo
Мова:	Inglês
Опубліковано:	BMC 2019-08-01
Серія:	Translational Neurodegeneration
Предмети:	Alzheimer’s disease (AD) Kallikrein-like peptidase (KLK) KLK6 KLK8 KLK10 Cerebral amyloid load
Онлайн доступ:	http://link.springer.com/article/10.1186/s40035-019-0168-6
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