Cardiac secreted HSP90α exacerbates pressure overload myocardial hypertrophy and heart failure

Sustained myocardial hypertrophy or left ventricular hypertrophy (LVH) triggered by pressure overload is strongly linked to adverse cardiovascular outcomes. Here, we investigated the clinical relationship between serum HSP90α (an isoform of HSP90) levels and LVH in patients with hypertension or aort...

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Detalhes bibliográficos

Principais autores:	Le Pan, Chenxing Huang, Xuejuan Jin, Jian Wu, Kejia Jin, Jingyi Lin, Ying Wang, Jianxuan Li, Chao Yin, Xiang Wang, Lei Zhang, Guoping Zhang, Hangming Dong, Junli Guo, Issei Komuro, Yuxiang Dai, Yunzeng Zou, Hui Gong
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2025-02-01
coleção:	Redox Biology
Assuntos:	HSP90 Cardiac hypertrophy Pressure overload Heart failure β-catenin
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2213231724004440
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