A Novel Magnetically Targeted Intramedullary (MagIC-TI) Xenograft Model for Precise Leukemia Modeling and Drug Resistance Evaluation in the Bone Marrow Niche

Acute myeloid leukemia (AML) remains a therapeutic challenge due to drug resistance and relapse, which are often driven by the protective bone marrow (BM) niche. Conventional xenograft models fail to adequately recapitulate this niche-specific pathophysiology. To overcome this limitation, a novel ma...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Qiusui Mai, Taosong Liu, Luxia Tang, Lihan Dai, Siyi Li, Jingyi Guo, Wen Xia, Lingxi Chen, Jiabao Wu, Jiawei Rong, Weishen Zhang, Jiaxing Zhang, Xiaojun Xu, Qianli Jiang
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Wiley 2026-01-01
Schriftenreihe:	Journal of Immunology Research
Online-Zugang:	http://dx.doi.org/10.1155/jimr/3236026
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!