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Dialdehyde Starch Cross-Linked Collagen with Heparin Conjugation: Characterization and Feasibility Study for Osteochondral Tissue Repair

Collagen is widely used in tissue engineering due to its excellent biocompatibility; however, its limited intrinsic mechanical strength restricts its application in load-bearing environments. This study introduces dialdehyde starch (DAS) as a biocompatible macromolecular cross-linker to enhance the...

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Main Authors: Jason K. Lee, Jihye Baek, Shawn P. Grogan, Tae-Hoon Koo, Darryl D. D’Lima
Format: Artigo
Language:Inglês
Published: MDPI AG 2025-10-01
Series:Gels
Subjects:
collagen
crosslinking
dialdehyde starch
heparin
growth factor
chondrocyte
Online Access:https://www.mdpi.com/2310-2861/11/11/850
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