Oxidative Stress Modifies the Levels and Phosphorylation State of Tau Protein in Human Fibroblasts

Since the tau protein is closely involved in the physiopathology of Alzheimer's disease (AD), studying its behavior in cellular models might lead to new insights on understanding this devastating disease at molecular levels. In the present study, primary cultures of human fibroblasts were establishe...

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Autors principals:	Alejandro Ibáñez-Salazar, Bernardo Bañuelos-Hernández, Ildefonso Rodríguez-Leyva, Erika Chi-Ahumada, Elizabeth Monreal-Escalante, María E. Jiménez-Capdeville, Sergio Rosales-Mendoza
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2017-09-01
Col·lecció:	Frontiers in Neuroscience
Matèries:	Alzheimer's disease fibroblasts tau protein oxidative stress phosphorylation state
Accés en línia:	http://journal.frontiersin.org/article/10.3389/fnins.2017.00495/full
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