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Transcriptomic alterations in cortical astrocytes following the development of post-traumatic epilepsy

Abstract Post-traumatic epilepsy (PTE) stands as one of the numerous debilitating consequences that follow traumatic brain injury (TBI). Despite its impact on many individuals, the current landscape offers only a limited array of reliable treatment options, and our understanding of the underlying me...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: John Leonard, Xiaoran Wei, Jack Browning, Erwin Kristobal Gudenschwager-Basso, Jiangtao Li, Elizabeth A. Harris, Michelle L. Olsen, Michelle H. Theus
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2024-04-01
Schriftenreihe:Scientific Reports
Schlagworte:
Seizures
Traumatic brain injury
Cst3
Gliosis
GFAP
Neuropeptide amidating enzyme
Online-Zugang:https://doi.org/10.1038/s41598-024-58904-z
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