DNMT3A in cancer: from epigenetic writer to oncogenic driver

Abstract Cancer is the leading cause of mortality, accounting for one in six deaths worldwide. Despite the emergence of new therapies, cancer mortality remains high. Cancer cells share many traits, such as reprogrammed metabolism and exacerbated proliferation. All these alterations are in part orche...

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Bibliographic Details

Main Authors:	Thomas Dupas, Enola Gautreau, Josianne Clavel, Noël J.-M. Raynal, Serge McGraw
Format:	Artigo
Language:	Inglês
Published:	BMC 2026-04-01
Series:	Clinical Epigenetics
Subjects:	DNA methylation Cancer DNA methyltransferase 3A Epigenetic
Online Access:	https://doi.org/10.1186/s13148-026-02127-8
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