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Comprehensive analysis of molecular markers linked to antimalarial drug resistance in Plasmodium falciparum in Northern, Northeastern and Eastern Uganda

Abstract Background In Uganda, antimalarial resistance in Plasmodium falciparum poses serious public health and treatment challenges. Globally, recent data have highlighted the roles of following genes in malaria resistance: Plasmodium falciparum dihydrofolate reductase (Pfdhfr), Plasmodium falcipar...

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Principais autores: Peter Olupot-Olupot, George Paasi, Thomas Katairo, Jimmy Patrick Alunyo, Alice Nakiyemba, Gilbert Gilibrays Ocen, Stephen Pande, Florance Alaroker, William Okiror, Emmaluel Ocen, Alex Oula, Charles Benard Okalebo, Ongodia Paul, Denis Amorut, Stephen Tukwasibwe, Susan Nabadda Ndidde, Isaac Sewanyana, Samuel L. Nsobya
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2025-06-01
coleção:Malaria Journal
Assuntos:
Antimalarial resistance
Uganda
Pfk13
Pfdhfr
Pfdhps Pfmdr1
Pfcrt
Acesso em linha:https://doi.org/10.1186/s12936-025-05439-x
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