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Selective Vulnerability of the Locus Coeruleus Noradrenergic System and its Role in Modulation of Neuroinflammation, Cognition, and Neurodegeneration

Locus coeruleus (LC) noradrenergic (NE) neurons supply the main adrenergic input to the forebrain. NE is a dual modulator of cognition and neuroinflammation. NE neurons of the LC are particularly vulnerable to degeneration both with normal aging and in neurodegenerative disorders. Consequences of th...

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Bibliografske podrobnosti
Principais autores: Andrew K. Evans, Erwin Defensor, Mehrdad Shamloo
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2022-11-01
Serija:Frontiers in Pharmacology
Teme:
Online dostop:https://www.frontiersin.org/articles/10.3389/fphar.2022.1030609/full
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