Heavy mechanical force decelerates orthodontic tooth movement via Piezo1-induced mitochondrial calcium down-regulation

Orthodontic tooth movement (OTM) depends on periodontal ligament cells (PDLCs), which sense biomechanical stimuli and initiate alveolar bone remodeling. Light (optimal) forces accelerate OTM, whereas heavy forces decelerate it. However, the mechanisms by which PDLCs sense biomechanical stimuli and a...

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Autores principales:	Ye Zhu, Xuehuan Meng, Qiming Zhai, Liangjing Xin, Hao Tan, Xinyi He, Xiang Li, Guoyin Yang, Jinlin Song, Leilei Zheng
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	KeAi Communications Co., Ltd. 2025-03-01
Colección:	Genes and Diseases
Materias:	Biomechanics Bone remodeling/regeneration Mechanotransduction Orthodontic tooth movement Periodontal ligament
Acceso en línea:	http://www.sciencedirect.com/science/article/pii/S2352304224002319
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