ERK3/MAPK6 dictates CDC42/RAC1 activity and ARP2/3-dependent actin polymerization

The actin cytoskeleton is tightly controlled by RhoGTPases, actin binding-proteins and nucleation-promoting factors to perform fundamental cellular functions. We have previously shown that ERK3, an atypical MAPK, controls IL-8 production and chemotaxis (Bogueka et al., 2020). Here, we show in human...

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Үндсэн зохиолчид:	Katarzyna Bogucka-Janczi, Gregory Harms, Marie-May Coissieux, Mohamed Bentires-Alj, Bernd Thiede, Krishnaraj Rajalingam
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	eLife Sciences Publications Ltd 2023-04-01
Цуврал:	eLife
Нөхцлүүд:	ERK3 MAPK RhoGTPases actin polymerization Arp2/3 cell shape /migration
Онлайн хандалт:	https://elifesciences.org/articles/85167
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!