Inhibiting Monoacylglycerol Lipase Suppresses RANKL-Induced Osteoclastogenesis and Alleviates Ovariectomy-Induced Bone Loss

Osteoporosis is a common chronic metabolic bone disease characterized by reduced trabecular bone and increased bone fragility. Monoacylglycerol lipase (MAGL) is a lipolytic enzyme to catalyze the hydrolysis of monoglycerides and specifically degrades the 2-arachidonoyl glycerol (2-AG). Previous stud...

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Váldodahkkit:	Hui Liu, Chuankun Zhou, Dahu Qi, Yutong Gao, Meipeng Zhu, Tenghui Tao, Xuying Sun, Jun Xiao
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Frontiers Media S.A. 2021-03-01
Ráidu:	Frontiers in Cell and Developmental Biology
Fáttát:	osteoporosis monoacylglycerol lipase JZL184 osteoclasts receptor activator of nuclear factor (NF)-κB ligand (RANKL)
Liŋkkat:	https://www.frontiersin.org/articles/10.3389/fcell.2021.640867/full
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