deSALT: fast and accurate long transcriptomic read alignment with de Bruijn graph-based index
Abstract The alignment of long-read RNA sequencing reads is non-trivial due to high sequencing errors and complicated gene structures. We propose deSALT, a tailored two-pass alignment approach, which constructs graph-based alignment skeletons to infer exons and uses them to generate spliced referenc...
Sábháilte in:
| Príomhchruthaitheoirí: | , , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe / Cruthaithe: |
BMC
2019-12-01
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| Sraith: | Genome Biology |
| Ábhair: | |
| Rochtain ar líne: | https://doi.org/10.1186/s13059-019-1895-9 |
| Clibeanna: |
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