A Novel Nonsense Variant in TBX15 Transcription Factor Suggests an Expanded Genetic Spectrum Of Submucous Cleft Palate

Introduction and aims: Submucous cleft palate (SMCP) is a congenital craniofacial malformation. While TBX22 is a known pathogenic gene, the potential role of TBX15 in SMCP remains unclear. This study aimed to investigate the genetic etiology of SMCP in a multigenerational family and explore the poss...

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Detalhes bibliográficos

Principais autores:	Yuting Wang, Kai Yu, Liangbin Huang, Yibin Cheng, Xiazhou Fu, Yaoting Ji
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2026-06-01
coleção:	International Dental Journal
Assuntos:	Nonsense variant Molecular genetics T-box 15 Craniofacial Submucous cleft palate
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0020653926001140
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